The action comedy is set in an apartment in Manhattan. After residents of the two legs to go to work and school, collect their pets for the day, consisting of hanging out, negotiate degrading stories about their owners, and help each other look wonderful to launch jobs as snacks. The head of the dog is a fast, suddenly threatened been the center of the universe of his master acute terrier home with Duke, overlooked a hybrid crude oil. The two soon find themselves on the streets of New York, where they meet-cute white rabbit Snowball. It turns out that Snowball is the leader of an army of animals that have been abandoned and are determined to return to mankind and all pet owners who love. Dogs must combat this plot and get back in time for dinner.